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Complete list of publications & preprints

Preprints
 

1. Mastrorosa FK, Rozanski AN, Harvey WT, Knuth J, Garcia G, Munson KMM, Hoekzema K, Logsdon GA†, Eichler EE†. Complete chromosome 21 centromere sequences from a Down syndrome family reveal size asymmetry and differences in kinetochore attachment. bioRxiv. 2024 Feb 26. doi: 10.1101/2024.02.25.581464.
†Co-corresponding author

 

2. Dubocanin D, Sedeno Cortes AE, Hartley GA, Ranchalis J, Agarwal A, Logsdon GA, Munson KM, Real T, Mallory BJ, Eichler EE, O’Neill RJ, Stergachis AB. Conservation of chromatin organization within human and primate centromeres. bioRxiv. 2023 April 20. doi: 10.1101/2023.04.20.537689

Publications
 

2024

 

​1. Logsdon GA, Rozanski AN, Ryabov F, Potapova T, Shepelev VA, Mao Y, Rautiainen M, Koren S, Nurk S, Porubsky D, Lucas JK, Hoekzema K, Munson KM, Gerton JL, Phillippy AM, Alexandrov IA, Eichler EE. The variation and evolution of complete human centromeres. Accepted at Nature. Available on bioRxiv. doi: 10.1101/2023.05.30.542849
 

2. Gambogi CW, Mer E, Brown DM, Arora UP, Yankson G, Gavade JN, Logsdon GA, Heun P, Glass JI, Black BE. Efficient formation of single-copy human artificial chromosomes. Accepted at Science. Available on bioRxiv. doi: 10.1101/2023.06.30.547284
 

3. Mao Y, Harvey WT, Porubsky D, Munson KM, Hoekzema K, Lewis AP, Audano PA, Rozanski A, Yang X, Zhang S, . . ., Logsdon GA, . . ., Eichler EE. Structurally divergent and recurrently mutated regions of primate genomes. Accepted at Cell. Available on bioRxiv. doi: 10.1101/2023.03.07.531415

2023

 

4. Gambogi CW, Pandey N, Dawick-McKenna JM, Arora UP, Liskovykh MA, Ma J, Lamelza P, Larionov V, Lampson MA, Logsdon GA, Dumont BL, Black BE. Centromere innovations within a mouse species. Sci Adv. 2023 Nov 17. doi: 10.1126/sciadv.adi5764. PMCID: PMC10651114
 

5. Rautiainen M, Nurk S, Walenz BP, Logsdon GA, Porubsky D, Rhie A, Eichler EE, Phillippy AM, Koren S. Verkko: telomere-to-telomere assembly of diploid chromosomes. Nat Biotechnol. 2023 Oct 24. doi: 10.1038/s41587-023-01662-6. PMCID: PMC10422740
 

6. Rhie A, Nurk S, Cechova M, Hoyt SJ, Taylor DJ, Altemose N, Hook PW, Koren S, Rautiainen M, Alexandrov IA, . . ., Logsdon GA, . . ., Phillippy AM. The complete sequence of a human Y chromosome. Nature. 2023 Aug 23. doi: 10.1038/s41586-023-06457-y. PMCID: PMC10752217
 

7. Hallast P, Ebert P, Loftus M, Yilmaz F, Audano PA, Logsdon GA, Bonder MJ, Zhou W, Hops W, Kim K, . . ., Lee C. Assembly of 43 diverse human Y chromosomes reveals extensive complexity and variation. Nature. 2023 Aug 23. doi: 10.1038/s41586-023-06425-6. PMCID: PMC10726138
 

8. Yang X, Wang X, Zou Y, Zhang S, Xia M, Fu L, Vollger MR, Chen N-C, Taylor DJ, Harvey WT, Logsdon GA, Meng D, Shi J, McCoy RC, Schatz MC, Li W, Eichler EE, Lu Q, Mao Y. Characterization of large-scale genomic differences in the first complete human genome. Genome Biol. 2023 Jul 4. doi: 10.1101/2022.12.17.520860. PMCID: PMC10320979
 

9. Vollger MR, DeWitt WS, Dishuck PC, Harvey WT, Guitart X, Goldberg ME, Rozanski AN, Lucas J, Asri M, The Human Pangenome Reference Consortium, . . ., Logsdon GA, Porubsky D, Paten B, Harris K, Hsieh PH, Eichler EE. Increased mutation and gene conversion within human segmental duplications. Nature. 2023 May 10. doi: 10.1038/s41586-023-05895-y. PMCID: PMC10172114
 

10. Dishuck PC, Rozanski AN, Logsdon GA, Eichler EE. GAVISUNK: Genome assembly validation via inter-SUNK distances in Oxford Nanopore reads. Bioinform. 2022 Nov 2. doi: 10.1093/bioinformatics/btac714. PMCID: PMC9805576

2022

 

11. Logsdon GA and Eichler EE. The dynamic structure and rapid evolution of human centromeric satellite DNA. Genes. 2022 Dec 28. doi: 10.3390/genes14010092. PMCID: PMC9859433
 

12. Jarvis ED, Formenti G, Rhie A, Guarracino A, Yang C, Wood J, Tracey A, Thibaud-Nissen F, Vollger MR, Porubsky D, Cheng H, Asri M, Logsdon GA, …, Eichler EE, Phillippy AM, Paten B, Howe K, Miga KH, Human Pangenome Reference Consortium. Semi-automated assembly of high-quality diploid human reference genomes. Nature. 2022 Oct 19. doi: 10.1038/s41586-022-05325-5. PMCID: PMC9668749
 

13. Altemose N, Logsdon GA*, Bzikadze AV*, Sidhwani P*, Langley SA*, Caldas GV*, Hoyt SH, Uralsky L, Ryabov FD, Shew CJ, …, Eichler EE, Phillippy AM, Timp W, Dennis MY, O’Neill RJ, Schatz MC, Pevzner PA, Diekhans M, Langley CH, Alexandrov IA, Miga KH. Complete genomic and epigenetic maps of human centromeres. Science. 2022 2022 April 1. doi: 10.1126/science.abl4178. PMCID: PMC9233505
*Authors contributed equally to the work

 

14. Nurk S, Koren S, Rhie A, Rautiainen M, Bzikadze AV, Mikheenko A, Vollger MR, Altemose N, Uralsky L, Gershman A, Aganezov S, Hoyt SJ, Diekhans M, Logsdon GA, …, Eichler EE, Miga KH, Phillippy AM. The complete sequence of a human genome. Science. 2022 April 1. doi: 10.1126/science.abj6987​. PMCID: PMC9186530
 

15. Gershman A, Sauria M, Hook PW, Hoyt SJ, Razaghi R, Koren S, Altemose N, Caldas GV, Vollger MR, Logsdon GA, Rhie A, Eichler EE, Schatz MA, O’Neill R, Phillippy AM, Miga KH, Timp W. Epigenetic patterns in a complete human genome. Science. 2022 April 1. doi: 10.1126/science.abj5089. PMCID: PMC9170183
 

16. McCartney AM, Shafin K, Alonge M, Bzikadze AV, Formenti G, Fungtammasan A, Howe K, Jain C, Koren S, Logsdon GA, Miga KH, Mikheenko A, Paten B, Shumate A, Soto DC, Sović I, Wood JMD, Zook JM, Phillippy AM, Rhie A. Chasing perfection: validation and polishing strategies for telomere-to-telomere genome assemblies. Nat Methods. 2022 April 1. doi: 10.1038/s41592-022-01440-3​. PMCID: PMC9812399
 

17. Hedouin S, Logsdon GA, Underwood JG, Biggins S. A transcriptional roadblock protects yeast centromeres. Nucleic Acids Res. 2022 Mar 7. doi: doi: 10.1093/nar/gkac11. PMCID: PMC9371891

2021

 

18. Giannuzzi G, Logsdon GA, Chatron N, Miller DE, Reversat DE, Munson KM, Hoekzema K, Bonnet-Dupeyron M-N, Pierre-Antoine RF, Baker CA, Sanlaville D, Eichler EE, Schluth-Bolard Caroline, Reymond A. Alpha satellite insertion close to an ancestral centromeric region. Mol Biol Evol. 2021 Dec 9. doi: 10.1101/2021.03.10.434819. PMCID: PMC8662618
 

19. Salinas-Luypaert C, Allu PK, Logsdon GA, Dawicki-McKenna JM, Gambogi CW, Fachinetti D, Black BE. Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub. Cell Rep. 2021 Nov 2. doi: 10.1016/j.celrep.2021.109924. PMCID: PMC8643106
 

20. Logsdon GA, Vollger MR, Hsieh P, Mao Y, Liskovykh MA, Koren S, Nurk S, Mercuri L, Dishuck PC, Rhie A, …, Miga KH, Phillippy AM, Eichler EE. The structure, function and evolution of a complete human chromosome 8. Nature. 2021 April 7. doi: 10.1038/s41586-021-03420-7. PMCID: PMC7877196

2020

 

21. Nurk S, Walenz BP, Rhie A, Vollger MR, Logsdon GA, Grothe R, Miga KH, Eichler EE, Phillippy AM, Koren S. HiCanu: accurate assembly of segmental duplications and allelic variants from high-fidelity long reads. Genome Res. 2020 August 14. doi: 10.1101/gr.263566.120. PMCID: PMC7545148
 

22. Miga KH, Koren S, Rhie A, Vollger MR, Gershman A, Bzikadze A, Brooks S, Howe E, Porubsky D, Logsdon GA, . . ., Eichler EE, Phillippy AM. Telomere-to-telomere assembly of a complete human X chromosome. Nature. 2020 July 14. doi: 10.1038/s41586-020-2547-7. PMCID: PMC7484160
 

23. Logsdon GA, Vollger MR, Eichler EE. Long-read human genome sequencing and its applications. Nat Rev Gen. 2020 June 5. doi: 10.1038/s41576-020-0236-x. PMCID: PMC7877196
 

24. Gambogi CW, Dawicki-McKenna J, Logsdon GA, Black BE. The unique kind of human artificial chromosome: bypassing the requirement for repetitive centromere DNA. Exp Cell Res. 2020 April 1. doi: 10.1016/j.yexcr.2020.11197. PMCID: PMC7253334
 

2019

 

25. Vollger MR*, Logsdon GA*, Audanao PA, Sulovari A, Porubsky D, Peluso P, Wenger AM, Concepcion GT, Kronenberg ZN, Munson KM, Baker C, Sanders AD, Spierings DCJ, Lansdorp PM, Surti U, Hunkapiller MW, Eichler EE. Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads. Ann Hum Genet. 2019 November 11. doi: 10.1111/ahg.12364
*Authors contributed equally to the work

 

26. Sulovari, A, Li R, Audano PA, Porubsky D, Vollger MR, Logsdon GA, Human Genome Structural Variation Consortium, Warren WC, Pollen AA, Chaisson M, Eichler EE. Human-specific tandem repeat expansion and differential gene expression during primate evolution. PNAS. 2019 October 28. doi: 10.1073/pnas.1912175116
 

27. Logsdon GA, Gambogi CW, Liskovykh MA, Barrey EJ, Larionov V, Miga KH, Heun P, Black BE. Human artificial chromosomes that bypass centromeric DNA. Cell. 2019 July 25. doi: 10.1016/j.cell.2019.06.006
 

28. Barra V, Logsdon GA, Scelfo A, Hoffman S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D. Phosphorylation of CENP-A on serine 7 does not control centromere function. Nat Commun. 2019 Jan 11. doi: 10.1038/s41467-018-08073-1

2018 and earlier

 

29. Logsdon GA and Black BE. The new normal of structure/function studies in the era of CRISPR/Cas9. Biochem J. 2018 May 15. doi: 10.1042/BCJ20170025
 

30. Wanat JJ, Logsdon GA, Driskill JH, Deng Z, Lieberman PM, Johnson FB. TERRA and the histone methyltransferase Dot1 cooperate to regulate replicative senescence in budding yeast. PLoS One. 2018 April 12. doi: 10.1371/journal.pone.019569
 

31. Guo LY, Allu PK, Zandarashvili L, McKinley KL, Sekulic N, Dawicki-McKenna JM, Fachinetti D, Logsdon GA, Jamiolkowski RM, Cleveland DW, Cheeseman IM, Black BE. Centromere maintenance is achieved by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome structural transition. Nat Commun. 2017 June 9. doi: 10.1038/ncomms15775
 

32. Fachinetti D*, Logsdon GA*, Abdullah A, Selzer EB, Cleveland DW, Black BE. CENP-A modifications on Ser68 and Lys124 are dispensable for establishment, maintenance, and long-term function of human centromeres. Dev Cell. 2017 January 9. doi: 10.1016/j.devcel.2016.12.014
*Authors contributed equally to the work

 

33. Falk SJ, Guo LY, Sekulic N, Smoak EM, Mani T, Logsdon GA, Gupta K, Jansen LET, Van Duyne GD, Vinogradov SA, Lampson MA, Black BE. CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere. Science. 2015 May 8. doi: 10.1126/science.1259308
 

34. Logsdon GA, Barrey EJ, Bassett EA, DeNizio JE, Guo LY, Panchenko T, Dawicki-McKenna JM, Heun P, Black BE. Both tails and the centromere targeting domain of CENP-A are required for centromere establishment. J Cell Biol. 2015 March 2. doi: 10.1083/jcb.201412011

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